Regulation of pyruvate dehydrogenase and pyruvate dehydrogenase phosphate phosphatase activity in rat epididymal fat-pads. Effects of starvation, alloxan-diabetes and high-fat diet.

نویسندگان

  • D Stansbie
  • R M Denton
  • B J Bridges
  • H T Pask
  • P J Randle
چکیده

1. Pyruvate dehydrogenase phosphate phosphatase activity in rat epididymal fat-pads was measured by using pig heart pyruvate dehydrogenase [32P]phosphate. About 80% was found to be extramitochondrial and therefore probably not directly concerned with the regulation of pyruvate dehydrogenase activity. The extramitochondrial activity was sensitive to activation by Ca2+, but perhaps less sensitive than the mitochondrial activity.

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عنوان ژورنال:
  • The Biochemical journal

دوره 154 1  شماره 

صفحات  -

تاریخ انتشار 1976